Home > Terms > English, UK (UE) > Krabbe disease
Krabbe disease
Krabbe disease (also known as globoid cell leukodystrophy or galactosylceramide lipidosis) is a rare, often fatal degenerative disorder that affects the myelin sheath of the nervous system. This condition is inherited in an autosomal recessive pattern. The disease is named for the Danish neurologist Knud Haraldsen Krabbe.
Symptoms begin between the ages of 3 and 6 months with irritability, fevers, limb stiffness, seizures, feeding difficulties, vomiting, and slowing of mental and motor development. In the first stages of the disease. Other symptoms include muscle weakness, spasticity, deafness, optic atrophy, optic nerve enlargement, blindness, paralysis, and difficulty when swallowing. Prolonged weight loss may also occur. In infants, the disease is generally fatal before age 2. Patients with late-onset Krabbe disease tend to have a slower progression of the disease and live significantly longer.
- Part of Speech: proper noun
- Synonym(s):
- Blossary:
- Industry/Domain: Health care
- Category: Incurable diseases
- Company:
- Product:
- Acronym-Abbreviation:
Other Languages:
Member comments
Terms in the News
Featured Terms
Contributor
Featured blossaries
Teresa Pelka
0
Terms
3
Blossaries
6
Followers
Teresa's glossary of psycholinguistics
Browers Terms By Category
- Dating(35)
- Romantic love(13)
- Platonic love(2)
- Family love(1)
Love(51) Terms
- Characters(952)
- Fighting games(83)
- Shmups(77)
- General gaming(72)
- MMO(70)
- Rhythm games(62)
Video games(1405) Terms
- Fiction(910)
- General literature(746)
- Poetry(598)
- Chilldren's literature(212)
- Bestsellers(135)
- Novels(127)
Literature(3109) Terms
- Aeronautics(5992)
- Air traffic control(1257)
- Airport(1242)
- Aircraft(949)
- Aircraft maintenance(888)
- Powerplant(616)