Home > Terms > English, UK (UE) > Autosomal dominant polycystic kidney
Autosomal dominant polycystic kidney
A genetic disorder with autosomal dominant inheritance characterised by multiple cysts in both kidneys and progressive deterioration of renal function. Type 1 is usually caused by a mutant gene at the PKD1 locus on the short arm of chromosome 16, though mutations elsewhere in the genome can also cause the disease. The age of onset of symptoms varies widely.
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