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Chronic idiopathic jaundice
A benign, autosomally recessive inherited hyperbilirubinemia characterised by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestional symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualise the biliary tract.
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