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Hepatic failure

1) Severe inability of the liver to function normally, as evidenced by severe jaundice and abnormal levels of ammonia, bilirubin, alkaline phosphatase, glutamic oxaloacetic transaminase, lactic dehydrogenase, and reversal of the albumin/globulin ratio.

2) The failure of the liver to detoxify chemicals in the body leading to a clinical disease.

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