Home > Terms > English, UK (UE) > Marker
Marker
1) An identifiable segment of DNA (e.g., RFLP, VNTR, microsatellite) with enough variation between individuals that its inheritance and co-inheritance with alleles of a given gene can be traced; used in linkage analysis.
2) A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes. DNA segments close to each other on a chromosome tend to be inherited together. Markers are used to track the inheritance of a nearby gene that has not yet been identified but whose approximate location is known. The marker itself may be a part of a gene or may have no known function.
- Part of Speech: noun
- Synonym(s):
- Blossary:
- Industry/Domain: Health care
- Category: Genetic disorders
- Company: National Library of Medicine
- Product:
- Acronym-Abbreviation:
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