If you ever happen to be running through rainforests, somewhere in Central or South America, never pick up a beautiful and colorful frog is a Dart Frog can be poison. This frog is probably the most poisonous animal on Earth. 2 Inches long (5 cm) Golden poison dart frog has enough poison to kill 20000 mice or 10 adults. Only 2 g of this deadly toxin (the number of which is at the head of a PIN) is capable of killing humans or other large mammals. They are called "Dart Frogs" because indigenous Indians use their toxic secretions to poison the tips of their blow Darts. Poison Dart Frogs keep their venom in their skins and will hurt or kill anyone who touches or eats it.