Hybridoma

Hybridoma

A cell that is useful in production of quantities of a monoclonal antibody; a fusion of a myeloma cell and a spleen lymphocyte that, like the myeloma cell, can divide in culture and, like the spleen cell, can produce antibodies. The use of HAT (hypoxanthine/ aminopterin/thymidine) medium allows selection of hybrids of myeloma cell mutants that lack hypoxanthine-guanine phosphoribosyltransferase and consequently cannot utilise hypoxanthine, with spleen cells, which do not proliferate in vitro.

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Part of Speech: noun
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Industry/Domain: Biology
Category: Biochemistry; Molecular biology
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hybridoma

Biology; Immunology

An immortalized hybrid cell resulting from the in vitro fusion of an antibody-secreting B cell with a myeloma; it secretes antibody without stimulation and proliferates ...

hybridomas

Biology; Immunology

Monoclonal antibodies are most commonly produced from hybridomas. These are hybrid cell lines formed by fusing a specific antibody-producing B lymphocyte with a myeloma cell that ...

hybridoma

Biotechnology; Genetic engineering

A hybrid cell, derived from a B (antibody producing) lymphocyte fused to a tumour cell, which grows indefinitely in tissue culture and is selected for the secretion of the ...

hybridoma

Plants; Plant pathology

A cell produced by the fusion of an antibody-producing cell and a lymphoma (cancer) cell for production of monoclonal antibodies.

hybridoma

Medical; Health care; Medicine

Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure monoclonal antibodies or T-cell ...

hybridoma

Biology; Biochemistry; Molecular biology

A cell that is useful in production of quantities of a monoclonal antibody; a fusion of a myeloma cell and a spleen lymphocyte that, like the myeloma cell, can divide in culture ...

calcareous

Biology; Biochemistry

The body parts of animals which contain calcium as shells, bones and exoskeleton and they protect the animals, are called as calcareous.

humus

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Humus is a dark material in the soil that is formed from decaying plants and leaves.

red blood cell

Biology; Biochemistry

A blood cell that carries oxygen and carbon dioxide to all body tissues is called as red blood cell.

rotten

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Anything that has gone bad; smelly; decayed; evil; unpleasant which is likely to break due to rot is called as rotten.

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anderogen

Biology; Biochemistry

One of the hormones that controls the physical development in males. Testosterone is an androgen.

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