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AIDS prevention & treatment

The prevention and treatment of acquired immune deficiency syndrome or AIDS, which is a disease of the human immune system caused by the human immunodeficiency virus (HIV). The illness interferes with the immune system, making people with AIDS much more likely to get infections. HIV is transmitted through direct contact with HIV-infected body fluids, such as blood, semen, and genital secretions, or from an HIV-infected mother to her child during pregnancy, birth, or breastfeeding (through breast milk).

Contributors in AIDS prevention & treatment

AIDS prevention & treatment

Cross resistance

Health care; AIDS prevention & treatment

Resistance to one or more drugs that occurs as a result of previous exposure to a similar drug. For example, HIV resistance to one non-nucleoside reverse transcriptase inhibitor (NNRTI) drug may ...

Rechallenge

Health care; AIDS prevention & treatment

Restarting a drug that was stopped because it was considered the likely cause of an adverse effect. When the drug is restarted, the person is closely monitored for any signs of the adverse effect.

Cardiovascular

Health care; AIDS prevention & treatment

Relating to or involving the heart and blood vessels. Use of some antiretroviral (ARV) drugs may increase the risk of cardiovascular disease.

Urticaria

Health care; AIDS prevention & treatment

Raised, swollen, itchy areas on the skin or mucous membranes, usually caused by an allergic reaction to a drug or food.

Biopsy

Health care; AIDS prevention & treatment

Removal of tissue, cells, or fluid from the body for examination under a microscope. Biopsies are used to diagnose disease.

Refractory

Health care; AIDS prevention & treatment

Resistant to treatment. For example, a refractory disease or condition is one that is not responding to treatment.

Phase I trial

Health care; AIDS prevention & treatment

The first step in testing an experimental drug in humans. Phase I trials evaluate the drug's safety and toxicity at different dose levels and determine drug pharmacokinetics. Because little is known ...

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