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Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Contributors in Cancer drugs

Cancer drugs

Hsp27 antisense oligonucleotide OGX-427

Pharmaceutical; Cancer drugs

A second-generation antisense oligonucleotide targeting heat shock protein 27 (Hsp27) with potential antitumor and chemosensitizing activities. Hsp27 antisense oligonucleotide OGX-427 suppresses ...

Antisense oligonucleotide ISIS EIF4ERx

Pharmaceutical; Cancer drugs

A second-generation antisense oligonucleotide targeting the eukaryotic translation initiation factor 4E (eIF4E) with potential antitumor activity. Antisense oligonucleotide ISIS EIF4ERx suppresses ...

Nedaplatin

Pharmaceutical; Cancer drugs

A second-generation cisplatin analogue with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive ...

E2F1 pathway activator ARQ 171

Pharmaceutical; Cancer drugs

A second-generation E2F1 pathway activator with potential antineoplastic activity. ARQ 171 induces the expression of E2F transcription factor 1, thereby activating the E2F1-mediated checkpoint ...

Epothilone KOS-1584

Pharmaceutical; Cancer drugs

A second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilises microtubules against ...

Monoclonal antibody CC49

Pharmaceutical; Cancer drugs

A second-generation murine monoclonal antibody based on the antibody B72. 3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed by gastric, breast, pancreatic, ...

Larotaxel

Pharmaceutical; Cancer drugs

A semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting microtubule assembly and stabilisation and preventing ...

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