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Cancer drugs
Drugs, agents used in the treatment of cancer or conditions related to cancer.
Industry: Pharmaceutical
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Cancer drugs
Pan-HER kinase inhibitor AC480
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule pan-HER tyrosine kinase inhibitor with potential antineoplastic and radiosensitizing activities. Pan-HER kinase inhibitor AC480 binds to and inhibits the human ...
Polo-like kinase 1 inhibitor NMS-1286937
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor NMS-1286937 selectively inhibits PLK1, inducing ...
Linifanib
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and ...
Apatinib
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial ...
C-Met inhibitor JNJ-38877605
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. C-Met inhibitor JNJ-38877605 selectively inhibits c-Met (mesenchymal-epithelial ...
JAK2 inhibitor TG101348
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule, ATP-competitive inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity. JAK2 inhibitor TG101348 competes with JAK2 as well as the ...
PDK1 inhibitor AR-12
Pharmaceutical; Cancer drugs
An orally bioavailable, small-molecule, celecoxib-derived inhibitor of phosphoinositide-dependent kinase-1 (PDK1) with potential antineoplastic activity. Devoid of any COX inhibiting activity, PDK1 ...