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Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Contributors in Cancer drugs

Cancer drugs

Pan-HER kinase inhibitor AC480

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule pan-HER tyrosine kinase inhibitor with potential antineoplastic and radiosensitizing activities. Pan-HER kinase inhibitor AC480 binds to and inhibits the human ...

Polo-like kinase 1 inhibitor NMS-1286937

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor NMS-1286937 selectively inhibits PLK1, inducing ...

Linifanib

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and ...

Apatinib

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial ...

C-Met inhibitor JNJ-38877605

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. C-Met inhibitor JNJ-38877605 selectively inhibits c-Met (mesenchymal-epithelial ...

JAK2 inhibitor TG101348

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule, ATP-competitive inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity. JAK2 inhibitor TG101348 competes with JAK2 as well as the ...

PDK1 inhibitor AR-12

Pharmaceutical; Cancer drugs

An orally bioavailable, small-molecule, celecoxib-derived inhibitor of phosphoinositide-dependent kinase-1 (PDK1) with potential antineoplastic activity. Devoid of any COX inhibiting activity, PDK1 ...

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