Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Contributors in Cancer drugs

Cancer drugs

An antibody-drug conjugate (ADC) directed against the tumour necrosis factor (TNF) receptor CD30 with potential antineoplastic activity. Brentuximab vedotin is generated by conjugating the humanised ...

Glembatumumab vedotin

Pharmaceutical; Cancer drugs

An antibody-drug conjugate, consisting of the fully human monoclonal antibody CR011 directed against glycoprotein NMB (GPNMB) and conjugated via a cathepsin B-sensitive valine-citrulline (vc) linkage ...

M-azidopyrimethamine

Pharmaceutical; Cancer drugs

An antifolate derived from diaminopyrimidine with cytotoxic properties. With a mechanism of action similar to that of methotrexate (MTX), m-azidopyrimethamine blocks tetrahydrofolate synthesis, ...

PNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine

Pharmaceutical; Cancer drugs

An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock ...

Racotumomab

Pharmaceutical; Cancer drugs

An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional ...

Tocladesine

Pharmaceutical; Cancer drugs

An antimetabolite and a chlorine derivative of the intracellular secondary messenger, cyclic adenosine 3,5-monophosphate (cAMP), with potential antineoplastic activity. Tocladesine appears to be ...

Tubulin-binding agent SSR97225

Pharmaceutical; Cancer drugs

An antimitotic tubulin-binding agent with potential antineoplastic activity. Tubulin-binding agent SSR97225 binds to tubulin, arresting the cell cycle at the G2/M checkpoint and preventing mitosis.