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Medicine
The science and art of healing that employs a variety of health care practices to maintain and restore health by the prevention and treatment of illness.
Industry: Health care; Medical
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Medicine
Thrombin-activated factor viii
Medical; Medicine
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably ...
Transcription factor ap2
Medical; Medicine
A family of DNA binding proteins that regulate expression of a variety of genes during cell differentiation and apoptosis. Family members contain a highly conserved carboxy-terminal basic ...
Arp3 protein
Medical; Medicine
A component of the Arp2-3 complex that is related in sequence and structure to actin and that binds ATP. It is expressed at higher levels than Arp2 protein and does not contain a profilin binding ...
Factor xia
Medical; Medicine
Activated form of factor XI. In the intrinsic pathway, factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (high molecular weight kininogen). Factor XIa then activates ...
Uphill transport
Medical; Medicine
The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy.
Fibrinoligase
Medical; Medicine
Activated form of factor XIII, a transglutaminase, which stabilises the formation of the fibrin polymer (clot) culminating the blood coagulation cascade.