Molecular biology

Molecular biology

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Molecular biology

Universal

Biology; Biochemistry

In molecular biology, descriptive of a tool that is generally useful, not limited to a specific DNA fragment or sequence; e.g. a universal adaptor is one that can be ligated to all DNA fragments.

Residue

Biology; Biochemistry

The part of a single sugar that appears in a polysaccharide; of a single amino acid in a protein; of a single nucleotide in a nucleic acid, etc.; usually the monomer minus the elements of water.

Cloning of ligand targets (COLT)

A strategy for screening phage cDNA libraries for genes that encode proteins that can bind a desired ligand. Phage which express the protein are identified on plates the ability to bind the labelled ...

Tetra-antennary

Biology; Biochemistry

Descriptive of a complex-type carbohydrate that has four unbranched oligosaccharide chains at a non-reducing end, often terminated by a sialic acid. Variants are tri-antennary and bi-antennary ...

Half-of-the-sites activity

Biology; Biochemistry

An extreme form of negative co-operativity shown by a multisubunit enzyme in which, as a substrate binds to the active site of one subunit, the affinity for the substrate of an adjacent subunit ...

Acceptor (3') splice site

Biology; Biochemistry

A site in pre-mRNA that corresponds to the 3'-end of the intron and the 5'-end of the next exon. The last two bases of the intron at the acceptor splice site are AG in most cases, but AC in some ...

Co-metabolism

Biology; Biochemistry

In microbial physiology, the metabolism of a xenobiotic which does not support growth. The phenomenon possibly involves the fortuitous metabolism of material due to partial non-specificity of key ...