Toxicology

Toxicology

A branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals or physical agents on living organisms, as well as the symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people.

Industry: Biology; Chemistry

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Toxicology

Critical dose

Biology; Toxicology

Dose of a substance at and above which adverse functional changes, reversible or irreversible, occur in a cell or an organ.

Critical study

Biology; Toxicology

Investigation yielding the no-observed-adverse-effect-level that is used by the USEPA as the basis of the reference dose.

Pivotal study

Biology; Toxicology

Investigation yielding the no-observed-adverse-effect-level that is used by the USEPA as the basis of the reference dose.

Deterministic

Biology; Toxicology

Term applied to health effects, the severity of which varies with the dose and for which a threshold is believed to exist.

Cometabolism

Biology; Toxicology

Process by which a normally non-biodegradable substance is biodegraded only in the presence of an additional carbon source.

Biological half life

Biology; Toxicology

For a substance the time required for the amount of that substance in a biological system to be reduced to one half of its value by biological processes, when the rate of removal is approximately ...

Carrier-linked prodrug

Biology; Toxicology

Compound that contains a temporary linkage between a given active substance and a transient carrier group, the latter producing improved physicochemical or pharmacokinetic properties and easily ...