Toxicology

Toxicology

A branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals or physical agents on living organisms, as well as the symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people.

Industry: Biology; Chemistry

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Toxicology

No-observed-adverse-effect level (NOAEL)

Biology; Toxicology

Greatest concentration or amount of a substance, found by experiment or observation, which causes no detectable adverse alteration of morphology, functional capacity, growth, development, or life ...

Lipophilic

Biology; Toxicology

Having an affinity for fat and high lipid solubility. Note: This is a physicochemical property which describes a partitioning equilibrium of solute molecules between water and an immiscible organic ...

Dominant half life

Biology; Toxicology

Half life of a fraction of a substance in a specific organ or compartment if it defines approximately the overall clearance rate for that substance at a specific time point.

Ecosystem

Biology; Toxicology

Grouping of organisms (micro-organisms, plants, animals) interacting together, with and through their physical and chemical environments, to form a functional entity within a defined environment.

Generally regarded as safe (GRAS)

Biology; Toxicology

Phrase used to describe the U.S. FDA philosophy that justifies approval of food additives that may not meet the usual test criteria for safety but have been used extensively and have not demonstrated ...

Endothelial

Biology; Toxicology

Pertaining to the layer of flat cells lining the inner surface of blood and lymphatic vessels, and the surface lining of serous and synovial membranes.