Home > Blossary: Addictive Drugs
A blossary of terms related to addictive drugs.

Category: Law

20 Terms

Created by: Silentchapel

Number of Blossarys: 95

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Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use.

Domain: Law enforcement; Category: Drug trafficking

Petidina está indicada para el tratamiento del dolor moderado a intenso y se entrega como una sal de clorhidrato en tabletas, como un jarabe, o por inyección intramuscular, intravenosa o subcutánea. Durante gran parte del siglo XX, petidina fue el opioide de elección para muchos médicos; en 1975 el 60% de los médicos lo prescrito para el dolor agudo y 22% para el dolor crónico severo. En comparación con la morfina, petidina creía ser más seguro, llevar un menor riesgo de adicción y ser superior para tratar el dolor asociado con espasmo biliar o cólico renal debido a sus supuestos efectos anticolinérgicos. Más tarde se descubrió que eran todos los mitos y que no llevaba un riesgo por lo menos igual de adicción, poseyó ningún efecto ventajoso sobre espasmo biliar o cólico renal en comparación a otros opiáceos y que, debido a su metabolito tóxico, norpethidine, fue más tóxico que otros opioides, especialmente durante el uso a largo plazo.

Domain: Law enforcement; Category: Drug trafficking

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