Atropates (370 BC – after 321 BC) was a Persian nobleman who served Darius III, then Alexander the Great, and eventually founded an independent kingdom and dynasty that was named after him.

Following the "Partition of Babylon" in 323 BCE, Media was divided into two parts: the greater portion in the south-east was to be governed by Peithon, a general of Perdiccas, while a smaller portion in the north west (principally around the Araxes River basin was given to Atropates. At some point thereafter, Atropates refused to convey allegiance to the diadochi and made his part of Media an independent kingdom, while his son-in-law Perdiccas was eventually murdered by Peithon in the summer of 320 BC.