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CK2 inhibitor CX-4945
An orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. CK2 inhibitor CX-4945 selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumour growth and survival.
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- Part of Speech: noun
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- Industry/Domain: Pharmaceutical
- Category: Cancer drugs
- Company: NCI
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