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COX-2 inhibitor
A type of nonsteroidal anti-inflammatory drug (NSAID) designed to be safer for the stomach than other NSAIDs. COX-2 inhibitors work by inhibiting hormonelike substances in the body that cause pain and inflammation without interfering with similar substances that protect the stomach lining. Celecoxib (Celebrex) is the only COX-2 inhibitor currently available. Two others, rofecoxib (Vioxx) and valdecoxib (Bextra), were withdrawn from the market when it was discovered they increased risks from heart disease.
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- Part of Speech: noun
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- Industry/Domain: Health care
- Category: Arthritis
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