213th Pope of the Catholic Church. Pontificate 1484 - 1492. His papacy was during what is known as the Little Ice Age. Instigated severe measures against magicians and witches in Germany. The grip of freezing weather, failing of crops, rising crime, and mass starvation was blamed on witches. He issued the bull to inquisitors Heinrich Kramer and Jacobus Sprenger to systemize the persecution of witches.