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N-methylformamide
A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionising radiation-induced DNA cross-linking in and terminal differentiation of tumour cells.
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- Part of Speech: noun
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- Industry/Domain: Pharmaceutical
- Category: Cancer drugs
- Company: NCI
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