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Home > Terms > English, UK (UE) > RNase cleavage
RNase cleavage
A method for detection of single base substitutions in DNA fragments. A labelled RNA probe that spans the target DNA sequence becomes susceptible to RNase A cleavage wherever there is any mismatch in sequences. The cleavage of the probe is detected upon gel electrophoresis.
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- Category: Biochemistry; Molecular biology
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