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Home > Terms > English, UK (UE) > X-linked recessive
X-linked recessive
A mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be expressed in males who are hemizygous for the gene mutation (i.e., they have only one X chromosome) and in females who are homozygous for the gene mutation (i.e., they have a copy of the gene mutation on each of their two X chromosomes). Carrier females who have only one copy of the mutation do not usually express the phenotype, although differences in X-chromosome inactivation can lead to varying degrees of clinical expression in carrier females.
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- Part of Speech: noun
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- Industry/Domain: Health care
- Category: Genetic disorders
- Company: National Library of Medicine
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