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Bio-availability in toxico- or pharmacokinetics
Ratio of the systemic exposure from extravascular (ev) exposure to that following intravenous (iv) exposure as described by the equation:
F = AevDiv / Biv Dev
where F (fraction of dose absorbed) is a measure of the bioavailability, A and B are the areas under the (plasma) concentration time curve following extravascular and intravenous administration respectively, and Dev and Div are the administered extravascular and intravenous doses.
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- Part of Speech: noun
- Synonym(s):
- Blossary:
- Industry/Domain: Biology; Chemistry
- Category: Toxicology
- Company: National Library of Medicine
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