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Home > Terms > English, UK (UE) > Double sieve
Double sieve
Descriptive of the mechanism for assuring correct charging of a tRNA by its amino acid activating enzyme. Only an amino acid that exactly fits the binding site will be ligated to the nucleic acid; those that are too large do not bind to the active site and those that are too small are hydrolysed.
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- Part of Speech: adjective
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- Category: Biochemistry; Molecular biology
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