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Home > Terms > English, UK (UE) > Excision
Excision
The removal of a section of double-stranded DNA that is faulty due to mutation or incorrect replication. The process includes incision, i.e. cleavage of the strand by an endonuclease and the action of a 5'-nucleotidase, followed by filling in by a polymerase and ligation. The E. coli DNA polymerase I has all these activities.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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