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Fluorescence in situ hybridization (FISH)
A method for visualisation of a genetic marker on a chromosome by use of a fluorescent labelled polynucleotide probe that hybridises to and indicates the locus of a gene on a chromosome during mitosis (metaphase). The methodology may also be used to locate and semi-quantitatively estimate the level of a specific mRNA at the sub-cellular level.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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