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Humanised antibody
A chimaeric immunoglobulin of human and non-human origin. In order to minimise the possibility of the chimaera being antigenic in humans, only the hypervariable regions of a non-human monoclonal antibody, which are responsible for its specificity, replace the homologous regions of a human immunoglobulin.
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- Part of Speech: noun
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- Category: Biochemistry; Molecular biology
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