Hypervariable region

Hypervariable region

A localised sequence of a variable region of an immunoglobulin that shows a particularly large variation in amino acid sequence compared with all other immunoglobulins; presumably the part of the immunoglobulin that interacts directly with the antigen.

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Part of Speech: noun
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Industry/Domain: Biology
Category: Biochemistry; Molecular biology
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Related terms

hypervariable regions

Biology; Immunology

Portions of the Ig or TCR chains that are highly variable in amino acid sequence from one molecule to another, and that together constitute the binding site for antigen.

hypervariable region

Biotechnology; Genetic engineering

The parts of both the heavy and light chains of an antibody molecule that enable it to bind to a specific site on an antigen.

hypervariable region

Biology; Biochemistry; Molecular biology

A localized sequence of a variable region of an immunoglobulin that shows a particularly large variation in amino acid sequence compared with all other immunoglobulins; presumably ...

immunoglobulin hypervariable region

Medical; Health care; Medicine

Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the immunoglobulin variable region that are highly divergent. Together the CDRs from the light and heavy ...

region

Software; Image processing

A connected subset of an image.

region

Language; Linguistics

That part of a spatial scene in which the figure may be found. A region is established by virtue of a spatial relation being designated as holding between a figure and reference ...