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Indium In 111 chimeric monoclonal antibody G250
A radioimmunoconjugate comprised of the chimeric monoclonal antibody G250 conjugated with the gamma-emitting radioisotope indium In 111. Indium I 111 chimeric monoclonal antibody G250 binds to G250, allowing the localization of G250-expressing tumour cells using gamma scintigraphy. Found in the majority of renal cell carcinomas (RCCs), G250 or carbonic anhydrase isozyme IX (CA IX) is a cell surface tumor-associated antigen (TAA).
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- Part of Speech: noun
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- Industry/Domain: Pharmaceutical
- Category: Cancer drugs
- Company: NCI
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