Home > Terms > English, UK (UE) > Maternal serum alpha-fetoprotein screening (MSAFP)

Maternal serum alpha-fetoprotein screening (MSAFP)

A blood test given to the expectant mother between weeks 15 and 18 of pregnancy to screen for an increased risk of the baby having a birth defect. High levels of MSAFP may be associated with a neural tube defect; low levels may be associated with Down syndrome. The test is used to decide whether a woman should undergo more invasive testing, such as an amniocentesis.

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