Home > Terms > English, UK (UE) > Polymorphism
Polymorphism
1) Natural variations in a gene, DNA sequence, or chromosome that have no adverse effects on the individual and occur with fairly high frequency in the general population.
2) Polymorphism involves one of two or more variants of a particular DNA sequence. The most common type of polymorphism involves variation at a single base pair. Polymorphisms can also be much larger in size and involve long stretches of DNA. Called a single nucleotide polymorphism, or SNP (pronounced "snip"), scientists are studying how SNPs in the human genome correlate with disease, drug response, and other phenotypes.
3) Difference in DNA sequence among individuals. Genetic variations occurring in more than 1% of a population would be considered useful polymorphisms for genetic linkage analysis.
- Part of Speech: noun
- Synonym(s):
- Blossary:
- Industry/Domain: Health care
- Category: Genetic disorders
- Company: National Library of Medicine
- Product:
- Acronym-Abbreviation:
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