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Positional candidate approach
A strategy for identification and cloning of a new gene; a combination of functional cloning, in which a property of the protein product (e.g. immunogenicity or liganding) is used to scan a cDNA library, and positional cloning, a more laborious approach that relies on chromosome walking from a nearby known sequence identified by genetic linkage.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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