Home > Terms > English, UK (UE) > Positional cloning
Positional cloning
The process that commences with searching for markers linked to a particular inherited trait, then using those markers to identify the approximate location of the gene responsible for the trait, and then using various cloning strategies (including chromosome walking, q.v.) to identify, isolate and characterise the gene. Originally, the strategy was called reverse genetics, a term that some consider to be a misnomer and misleading.
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- Part of Speech: noun
- Synonym(s):
- Blossary:
- Industry/Domain: Biotechnology
- Category: Genetic engineering
- Organization: FAO
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