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Rack model
A model for interaction of a protein with a ligand in which the protein binds preferentially with one of several conformers of the ligand; especially enzyme action in which the substrate is proposed to bind to a conformation of the enzyme that produces a strain on the substrate, focused on the bond that must be broken to effect catalysis; also known as the handshake model, and contrasted with the lock and key theory, in which both protein and ligand are imagined to be inflexible.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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