Site-directed mutagenesis

Site-directed mutagenesis

A technique to alter deliberately a structural gene to insert a desired point mutation. A synthetic polynucleotide that contains the genetic alteration is used as an imperfectly fitting primer in replication and the completed (-)-strand incorporates the mutation.

This is auto-generated content. You can help to improve it.

0 0

Improve it

Add an image

Part of Speech: noun
Synonym(s):
Blossary:
Industry/Domain: Biology
Category: Biochemistry; Molecular biology
Company:
Product:
Acronym-Abbreviation:

Collect to Blossary

Other Languages:

Related terms

site-directed mutagenesis

Biotechnology; Genetic engineering

The introduction of base changes - mutations - into a piece of DNA at a specific site, using recombinant DNA methods.

site-directed mutagenesis

Agriculture; General agriculture

Mutagenesis where the mutation is caused by in vitro induction directed at a specific site in a DNA molecule. The most common method involves use of a chemically synthesized ...

site directed mutagenesis

Medical; Health care; Medicine

Genetically engineered mutagenesis at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.

site-directed mutagenesis

Biology; Biochemistry; Molecular biology

A technique to alter deliberately a structural gene to insert a desired point mutation. A synthetic polynucleotide that contains the genetic alteration is used as an imperfectly ...