Home > Terms > English, UK (UE) > Site-directed mutagenesis
Site-directed mutagenesis
A technique to alter deliberately a structural gene to insert a desired point mutation. A synthetic polynucleotide that contains the genetic alteration is used as an imperfectly fitting primer in replication and the completed (-)-strand incorporates the mutation.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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