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stathmin

A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of signal transduction pathways. Phosphorylation of stathmin occurs during cell cycle progression, and stathmin functions as a microtubule-destabilizing protein that promotes microtubule depolymerization during interphase and late mitosis. Stathmin is expressed at very high levels in a variety of human cancers.

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