yeast artificial chromosome

yeast artificial chromosome

Yeast artificial chromosome (YAC) is a human-engineered DNA molecule used to clone DNA sequences in yeast cells. YACs are often used in connection with the mapping and sequencing of genomes. Segments of an organism's DNA, up to one million base pairs in length, can be inserted into YACs. The YACs, with their inserted DNA, are then taken up by yeast cells. As the yeast cells grow and divide, they amplify the YAC DNA, which can be isolated and used for DNA mapping and sequencing.

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Part of Speech: noun
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Industry/Domain: Health care
Category: Genetic disorders
Company: National Library of Medicine
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yeast artificial chromosome (YAC)

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A vector used to clone DNA fragments from 300 kb to one megabase (unit of length for DNA fragments equal to one million nucleotides) in length. These clones can span large ...

yeast artificial chromosome (YAC)

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YAC is used as a vector system for cloning DNA fragments that can be hundreds of kilobases long. Linear cloning vectors constructed from essential elements of yeast chromosomes. ...

yeast artificial chromosome (YAC)

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A cloning vector in which DNA fragments several hundred kilobase pairs long can be cloned in yeast. A YAC is a linear vector with a yeast telomere at each end, a centromere, a ...

yeast artificial chromosome (YAC)

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Constructed from yeast DNA, it is a vector used to clone large DNA fragments. See also: cloning vector, cosmid.

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