Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

Autoimmune disease

Biology; Biochemistry

A failure of tolerance; the reaction of an individual's immune system towards some of the individual's own proteins as if they were foreign proteins, e.g. myasthenia gravis, rheumatoid arthritis.

Erybraedin C

Biology; Biochemistry

A pterocarpan purified from the plant Bituminaria bituminosa that inhibits both the cleavage and religation activities of human topoisomerase I and has been shown to have an anti-tumor activity.

Pleiotropism

Biology; Biochemistry

A characteristic of action of some hormones; expression of several activities, e.g. the action of insulin both to promote glucose uptake by skeletal muscle cells and to promote protein synthesis.

Universal

Biology; Biochemistry

In molecular biology, descriptive of a tool that is generally useful, not limited to a specific DNA fragment or sequence; e.g. a universal adaptor is one that can be ligated to all DNA fragments.

Residue

Biology; Biochemistry

The part of a single sugar that appears in a polysaccharide; of a single amino acid in a protein; of a single nucleotide in a nucleic acid, etc.; usually the monomer minus the elements of water.

Cloning of ligand targets (COLT)

A strategy for screening phage cDNA libraries for genes that encode proteins that can bind a desired ligand. Phage which express the protein are identified on plates the ability to bind the labelled ...

Tetra-antennary

Biology; Biochemistry

Descriptive of a complex-type carbohydrate that has four unbranched oligosaccharide chains at a non-reducing end, often terminated by a sialic acid. Variants are tri-antennary and bi-antennary ...