Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Contributors in Cancer drugs

Cancer drugs

A semisynthetic analogue of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Peplomycin forms complexes with iron that ...

Lurtotecan

Pharmaceutical; Cancer drugs

A semisynthetic analogue of camptothecin with antineoplastic activity. Lurtotecan selectively stabilises the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. As a ...

7-cyanoquinocarcinol

Pharmaceutical; Cancer drugs

A semisynthetic analogue of the Streptomyces melanovinaceus-derived tetracyclic antitumor antibiotic quinocarmycin with potential antineoplastic activity. Quinocarmycin belongs to the ...

11C topotecan

Pharmaceutical; Cancer drugs

A semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata radiolabeled with carbon 11 (11C) with antineoplastic and ...

Detorubicin

Pharmaceutical; Cancer drugs

A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and ...

SiRNA-expressing SV40 vector

Pharmaceutical; Cancer drugs

A simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential antineoplastic activity. The expression of siRNA in target tumour cells transfected with an ...

LMB-7 immunotoxin

Pharmaceutical; Cancer drugs

A single chain chimeric protein consisting of a monoclonal antibody fragment attached to a portion of the Pseudomonas exotoxin A. LMB-7 immunotoxin attaches to B3, a Lewis Y-related carbohydrate ...