Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Contributors in Cancer drugs

Cancer drugs

An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby ...

Serine protease inhibitor WX-671

Pharmaceutical; Cancer drugs

An orally bioavailable, 3-amidinophenylalanine-derived, second generation serine protease inhibitor prodrug targeting the human urokinase plasminogen activator (uPA) system with potential ...

Aurora kinase inhibitor PF-03814735

Pharmaceutical; Cancer drugs

An orally bioavailable, ATP-competitive, reversible small-molecule Aurora kinase inhibitor with potential antineoplastic activity. Aurora kinase inhibitor PF-03814735 binds to and inhibits Aurora ...

BRAF(V600E) kinase inhibitor RO5185426

Pharmaceutical; Cancer drugs

An orally bioavailable, ATP-competitive, small-molecule inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. BRAF(V600E) kinase inhibitor RO5185426 selectively binds to the ...

Hsp90 inhibitor XL888

Pharmaceutical; Cancer drugs

An orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor XL888 specifically binds to Hsp90, ...

Hedgehog pathway inhibitor IPI-926

Pharmaceutical; Cancer drugs

An orally bioavailable, cyclopamine-derived inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway inhibitor IPI-926 binds to and inhibits the ...

Aurora kinase inhibitor MLN8054

Pharmaceutical; Cancer drugs

An orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Auora kinase inhibitor MLN8054 binds ...