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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
Prostaglandins
Biology; Immunology
Prostaglandins, like leukotrienes, are lipid products of the metabolism of arachidonic acid that have a variety of effects on a variety of tissues, including activities as inflammatory mediators.
Adoptive immunity
Biology; Immunology
Adoptive immunity is immunity conferred on a naive or irradiated recipient by transfer of lymphoid cells from an actively immunised donor. This is called adoptive transfer or adoptive immunization.
Thymocytes pair with a surrogate α chain called pTα
Biology; Immunology
In T-cell development, TCR β chains expressed by CD44lowCD25+thymocytes pair with a surrogate α chain called pTα (pre-T-cell α) to form a pre-T-cell receptor that exits the endoplasmic reticulum via ...
Two-dimensional gel electrophoresis,
Biology; Immunology
In two-dimensional gel electrophoresis, proteins are separated by isoelectric focusing in one dimension, followed by SDS-PAGE on a slab gel at right-angles to the first dimension. This can separate ...
Adenosine deaminase deficiency
Biology; Immunology
The enzyme defect adenosine deaminase deficiency leads to the accumulation of toxic purine nucleosides and nucleotides, resulting in the death of most developing lymphocytes within the thymus. It is ...
Mixed lymphocyte reaction
Biology; Immunology
When lymphocytes from two unrelated individuals are cultured together, the T cells proliferate in response to the allogeneic MHC molecules on the cells of the other donor. This mixed lymphocyte ...
MHC class II transactivator
Biology; Immunology
The protein that activates the transcription of MHC class II genes, the MHC class II transactivator (CIITA), is one of several defective genes in the disease bare lymphocyte syndrome, in which MHC ...
