Toxicology

Toxicology

A branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals or physical agents on living organisms, as well as the symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people.

Industry: Biology; Chemistry

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Toxicology

Edoema

Biology; Toxicology

Presence of abnormally large amounts of fluid in intercellular spaces of body tissues.

Deoxyribonucleic acid (DNA) repair

Biology; Toxicology

Restoration of the molecular structure of DNA after it has been damaged by a chemical or physical agent: this may involve direct DNA damage reversal, base excision repair, nucleotide excision repair, ...

Cell-mediated hypersensitivity

Biology; Toxicology

State in which an individual reacts with allergic effects caused by the reaction of antigen-specific T-lymphocytes following exposure to a certain substance (allergen) after having been exposed ...

Basement membrane

Biology; Toxicology

Specialised layers of extra-cellular matrix (basal laminae) that separate epithelial tissue from underlying connective tissue: cancer cells must break through the basement membrane in order to ...

Bilirubin

Biology; Toxicology

Orange-yellow pigment, a breakdown product of heme-containing proteins (hemoglobin, myoglobin, cytochromes), which circulates in the blood plasma bound to albumin or as water soluble glucuronide ...

Benchmark concentration (BMC)

Biology; Toxicology

Statistically calculated lower 95% confidence limit on the concentration that produces a defined response (called the benchmark response or BMR, usually 5% or 10%) for an adverse effect compared to ...

Anaemia

Biology; Toxicology

Condition in which there is a reduction in the number of red blood cells or amount of haemoglobin per unit volume of blood below the reference interval for a similar individual of the species under ...