Roxana was a Bactrian (Persian Empire) princess and the second wife of Alexander the Great. She was born earlier than the year 343 BC.

Roxana bore him a posthumous son called Alexander IV Aegus,

after Alexander's sudden death in 323 BC. She and her son were protected by Alexander's mother, Olympias, in Macedonia, but her assassination in 316 BC allowed Cassander to seek kingship. Since Alexander IV Aegus was the legitimate heir to the Alexandrian empire, Cassander ordered him and Roxana assassinated about 310 BC.