Home > Terms > English, UK (UE) > Denaturing gradient gel electrophoresis (DGGE)
Denaturing gradient gel electrophoresis (DGGE)
Identification of mutations by electrophoresis of double-stranded DNA samples through a denaturing gradient, such as urea. Certain mutations affect the migration pattern by changing the point in the gel at which the DNA denatures; mutant sequences can be distinguished from wild-type sequences by comparing the electrophoretic pattern.
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- Part of Speech: noun
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- Industry/Domain: Medical
- Category: Human genome
- Company: National Library of Medicine
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