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Desmosome
1) Desmosomes are intercellular anchoring junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells. Desmosomes assemble in response to cell-cell contact and raised levels of extracellular calcium. Sensitivity to calcium levels is lost as desmosomes mature.
2) A specialised local thickening of the plasma membrane of an epithelial cell that serves to anchor contiguous cells together.
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- Part of Speech: noun
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- Industry/Domain: Medical
- Category: Human genome
- Company: National Library of Medicine
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