Exonuclease

Exonuclease

An enzyme that cleaves nucleotides one at a time from an end of a polynucleotide chain. An enzyme that hydrolyzes phosphodiester bonds from either the 3' or 5' terminus of a polynucleotide molecules.

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Industry/Domain: Legal services
Category: DNA forensics
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exonuclease

Biotechnology; Genetic engineering

An enzyme that digests DNA or RNA, beginning at the ends of strands. It requires a free end in order to degrade a DNA or RNA molecule. 5´ exonucleases require a free 5´ end and ...

exonuclease

Legal services; DNA forensics

An enzyme that cleaves nucleotides one at a time from an end of a polynucleotide chain. An enzyme that hydrolyzes phosphodiester bonds from either the 3' or 5' terminus of a ...

exonuclease

Biology; Genome

An enzyme that cleaves nucleotides sequentially from free ends of a linear nucleic acid substrate..

exonuclease V

Medical; Health care; Medicine

An ATP-dependent exodeoxyribonuclease that cleaves in either the 5'- to 3'- or the 3'- to 5'-direction to yield 5'-phosphooligonucleotides. It is primarily found in bacteria.

exonucleases

Medical; Health care; Medicine

Enzymes that catalyze the release of mononucleotides by the hydrolysis of the terminal bond of deoxyribonucleotide or ribonucleotide chains.

5' exonuclease

Medical; Medicine

A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides. It has low activity towards POLYnucleotides and ...

personal service

Legal services; DNA forensics

Delivering a summons, complaint, notice to quit tenancy or other legal document which must be served by handing it directly to the person named in the document. The delivery of ...

phenol

Legal services; DNA forensics

A chemical used in organic extraction. Polysaccharides and proteins are soluble in phenol, allowing for their separation from DNA. C6H5OH. See figure to the right.

phenotype

Legal services; DNA forensics

The detectable outward manifestations of a specific genotype; the physical characteristics of a living object.

pigmentation

Legal services; DNA forensics

Coloration or discoloration by formation or deposition of pigment in the tissues. In a forensic hair examination, the description of the aggregation, distribution, and density of ...

pili annulati

Legal services; DNA forensics

Pili annulati is a hair disorder that results in ringed or banded hair, alternating bright and dark bands in the hair shaft. The dark bands are a manifestation of the abnormal air ...

pili bifurcati

Legal services; DNA forensics

A genetic hair disorder characterized by two hairs joined at the shaft along their entire length.

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