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Host-guest protocol
An experiment designed to evaluate the contribution of different amino acids at a single sequence position to the stability of a polypeptide. Site-directed mutagenesis or synthetic chemical techniques are used to construct polypeptides that differ only at a single sequence position. Quantification of the stability of the polypeptide measures the contribution of each possible amino acid.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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