5 TermsHome > Terms > English, UK (UE) > Plevitrexed
Plevitrexed
An orally bioavailable, small molecule, non-polyglutamatable, antifolate quinazoline derivative thymidine synthetase inhibitor with potential antineoplastic activity. Plevitrexed is transported into the cell via the physiological reduced folate carrier (RFC) system. Intracellularly, this agent selectively binds to the folate binding site of thymidylate synthase and inhibits thymidine synthesis, which may result in DNA synthesis inhibition and apoptosis.
This is auto-generated content. You can help to improve it.
0
0
Improve it
- Part of Speech: noun
- Synonym(s):
- Blossary:
- Industry/Domain: Pharmaceutical
- Category: Cancer drugs
- Company: NCI
- Product:
- Acronym-Abbreviation:
Other Languages:
Member comments
Terms in the News
Featured Terms
Industry/Domain: History Category: American history
Attack on Pearl harbour
In the morning of December 7, 1941, Japan launched a major surprise strike against the United States naval base at Pearl harbour that killed 2,000 ...
Contributor
Featured blossaries
anton.chausovskyy
0
Terms
25
Blossaries
4
Followers
Intro to Psychology
Category: Education 1 5 Terms
5 Terms
Andronikos Timeliadis
0
Terms
1
Blossaries
0
Followers
Food products of Greece
Category: Other 1 2 Terms
2 TermsBrowers Terms By Category
- Authors(2488)
- Sportspeople(853)
- Politicians(816)
- Comedians(274)
- Personalities(267)
- Popes(204)
People(6223) Terms
- Misc restaurant(209)
- Culinary(115)
- Fine dining(63)
- Diners(23)
- Coffehouses(19)
- Cafeterias(12)
Restaurants(470) Terms
- Electricity(962)
- Gas(53)
- Sewage(2)
Utilities(1017) Terms
- News(147)
- Radio & TV broadcasting equipment(126)
- TV equipment(9)
- Set top box(6)
- Radios & accessories(5)
- TV antenna(1)