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Unfolded protein response (UPR)
The cell's graded response to the presence of unfolded or misfolded proteins; initially, activation of the genes that support endoplasmic reticulum-associated protein degradation, then, if the system is incapable of coping with the magnitude of the challenge, apoptosis to sacrifice the entire cell.
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- Part of Speech: noun
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- Industry/Domain: Biology
- Category: Biochemistry; Molecular biology
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